Angiotensin I Converting Enzyme 2 (ACE2) Inhibitor Screening Kit
SKU: E-BC-D001
Angiotensin I Converting Enzyme 2 (ACE2) Inhibitor Screening Kit
SKU # | E-BC-D001 |
Detection Instrument | Fluorescnece Microplate Reader (Ex/Em=325 nm/395 nm) |
Detection Method | Fluorescence Method |
Detection Principle
Angiotensin converting enzyme 2 (ACE2) is an important component of the renin angiotensin system (RAS). ACE2 is a negative regulatory factor of RAS, which can balance multiple functions of ACE. By regulating angiotensin II, ACE2 can cleave angiotensin II into Ang1-7, which has active effects such as protecting the heart and relaxing blood vessels. It is also one of the key active receptors in the field of pharmaceutical science research. The principle of this kit is that ACE2 catalyzes the decomposition of substrates, releasing fluorescent products. Adding inhibitors can inhibit the fluorescence value, and the inhibition ability of inhibitors can be determined by the fluorescence value
Performance Characteristics
Detection method | Fluorescence method |
Assay type | Inhibition Rate |
Assay time | 45 min |
Precision | Average inter-assay CV: 10.500%Average intra-assay CV: 0.800% |
Storage | -20℃ |
Valid period | 12 months |