IBT Bioservices SARS-COV-2, Virus Like Particles (Alpha (B.1.1.7))

IBT Bioservices SARS-COV-2, Virus Like Particles (Alpha (B.1.1.7))

Summary

• SARS-CoV-2 Virus Like Particles (Alpha (B.1.1.7)) The hybrid alpha-pseudovirus for SARS-CoV-2 (Ha-CoV-2) is a newly developed SARS-CoV-2 virus-like particle (VLP) that encapsulates an alphavirus-derived RNA genome for rapid report expression (luciferase or GFP) in target cells (Hetrick et al., 2022). Different from commonly used S protein pseudotyped lenti- or vesicular stomatitis virus (VSV)-pseudoviruses, Ha-CoV-2 is assembled with all 4 structural proteins (S, M, N, and E) of SARS-CoV-2, and contains a reporter genome derived from an alphavirusbased vector for rapid (6 hours) and robust expression of reporter genes. The alphavirus vector does not contain any of the structural proteins from the authentic virus and the alpha-pseudovirus particles are single-cycle. Spike mutations: Spike A570D, Spike D614G, Spike D1118H, Spike H69del, Spike N501Y, Spike P681H, Spike S982A, Spike T716I, Spike V70del, Spike Y145del Size:
• 25 X 200 µL ~100 wells/96 well plate
• 60x Conc. 5 x 100 µL
• Reporter: Available with Firefly luciferase, GFP, or RFP   Intended for research use only, not for human, therapeutic, or diagnostic applications. 

Overview

Properties

• Form: Liquid
• Formulation: Available upon request
• Storage: -80°C
• Concentration: 1X Concentrated

MSE Supplies is an authorized distributor of IBT Bioservices products.