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MSE PRO AdBrettPhos, 97% Purity– MSE Supplies LLC

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MSE PRO 2-(Di-1-adaMantylphosphino)-3, 6-diMethoxy-2', 4', 6'-tri-i-propyl-1, 1'-biphenyl (AdBrettPhos), 97% Purity - MSE Supplies LLC

MSE PRO 2-(Di-1-adaMantylphosphino)-3, 6-diMethoxy-2', 4', 6'-tri-i-propyl-1, 1'-biphenyl (AdBrettPhos), 97% Purity

SKU: CM1342

  • $ 41995

MSE PRO™ 2-(Di-1-adaMantylphosphino)-3, 6-diMethoxy-2', 4', 6'-tri-i-propyl-1, 1'-biphenyl (AdBrettPhos), 97% Purity

MSE PRO™ 2-(Di-1-adaMantylphosphino)-3, 6-diMethoxy-2', 4', 6'-tri-i-propyl-1, 1'-biphenyl (AdBrettPhos) is a bidentate phosphine ligand that has been used in various palladium-catalyzed cross-coupling reactions. The rigid, bulky structure of AdBrettPhos can help stabilize the active metal catalyst and influence the selectivity of cross-coupling reactions. Additionally, the combination of steric bulk and electronic properties makes AdBrettPhos a versatile ligand that can facilitate important organic transformations in transition metal catalysis.

MSE Supplies offers various catalysts and ligands of coupling reaction. Please contact us for customization or bulk orders.

Technical Specifications:

CAS No. 1160861-59-5 
Chemical name 2-(Di-1-adaMantylphosphino)-3, 6-diMethoxy-2', 4', 6'-tri-i-propyl-1, 1'-biphenyl
Synonym(s)
  • AdBrettPhos
  • bis(1-adamantyl)-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane
Molecular formula C43H61O2P 
Pack size 500 mg (CM1342); 1 g (CM1343)
Molecular weight 640.92 g/mol
Purity 97 %
Melting point 231-235 °C
Appearance White to off-white solid
Storage  2-8 °C, protect from light, stored under nitrogen


References:

[1] Xue, B., Shen, J., Manna, S., Doppiu, A., & Gooßen, L. J. (2023). Selective Monoarylation of Ammonium Triflate with Aryl Chlorides Catalyzed by [Pd (β‐MeNAP) Br] 2 and AdBrettPhos. Advanced Synthesis & Catalysis, 365(20), 3473-3477.

[2] Lee, H. G., Milner, P. J., & Buchwald, S. L. (2013). An improved catalyst system for the Pd-catalyzed fluorination of (hetero) aryl triflates. Organic letters, 15(21), 5602-5605.