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MSE PRO 3-Maleimidopropionic acid, ≥99.0% Purity– MSE Supplies LLC

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MSE PRO 3-Maleimidopropionic acid, ≥99.0% Purity - MSE Supplies LLC

MSE PRO 3-Maleimidopropionic acid, ≥99.0% Purity

SKU: CM1389

  • $ 31925

MSE PRO™ 3-Maleimidopropionic acid, ≥99.0% Purity

MSE PRO™ 3-Maleimidopropionic acid is primarily employed as a crosslinking agent for the modification and conjugation of biomolecules, such as proteins, peptides, and antibodies. The maleimide group selectively reacts with free sulfhydryl groups present in cysteine residues, forming a stable thioether linkage. This property allows for site-specific labeling, immobilization, or conjugation of biomolecules with various probes, fluorophores, or other functional groups. It is a valuable tool in proteomics, bioconjugation, and the development of diagnostic and therapeutic agents, enabling the creation of bioconjugates with enhanced properties or functionalities.

MSE Supplies offers various N-heterocyclic drug small molecules and other chemical reagents. Please contact us for bulk orders.

Technical Specifications:

CAS No. 7423-55-4
Chemical name 3-Maleimidopropionic acid
Synonym(s)
  • 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid
  • N-Maleoyl-beta-alanine
Molecular formula C7H7NO4     
Pack size 25 g (CM1389); 100 g (CM1390)
Molecular weight 169.13 g/mol
Purity 99.96% (HPLC) 
Boiling point 382.5±25.0 °C (Predicted)
Melting point  103-106 °C
Density   1.473±0.06 g/cm3 (Predicted)
pKa 4.18±0.10 (Predicted)
Appearance White to off-white solid
Storage  2-8°C, protect from light


References:

[1] Khan, M. I., Baloch, M. K., & Ashfaq, M. (2004). Biological aspects of new organotin (IV) compounds of 3-maleimidopropionic acid. Journal of organometallic chemistry, 689(21), 3370-3378.

[2] Chowdhury, S. M., Munske, G. R., Siems, W. F., & Bruce, J. E. (2005). A new maleimide‐bound acid‐cleavable solid‐support reagent for profiling phosphorylation. Rapid Communications in Mass Spectrometry: An International Journal Devoted to the Rapid Dissemination of Up‐to‐the‐Minute Research in Mass Spectrometry, 19(7), 899-909.