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MSE PRO 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine, 98.0% Purity– MSE Supplies LLC

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MSE PRO 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine, 98.0% Purity - MSE Supplies LLC

MSE PRO 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine, 98.0% Purity

SKU: CM1332

  • $ 33995

MSE PRO™ 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine, 98.0% Purity

MSE PRO™ 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine is a key small molecule building block within the pyrrolidine family that has significant applications in the development of atypical antipsychotic drugs. This compound exhibits high affinity for the 5-HT1A and 5-HT3 serotonin receptors, making it a valuable pharmacophore for the design of novel antipsychotic agents. The unique bicyclic structure and the presence of the methylated azabicyclic moiety confer this molecule with distinct pharmacological properties that are advantageous for its use in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients.

MSE Supplies offers various N-heterocyclic drug small molecules. Please contact us for bulk orders.

Technical Specifications:

CAS No. 98998-25-5
Chemical name 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine
Synonym(s)
  • 8-Azabicyclo[3.2.1]octan-3-amine
  • 3-Aminotropan
Molecular formula C8H16N2 
Pack size

 5 g (CM1332)
Molecular weight 140.23 g/mol
Melting point 124-125 °C 
Density  0.990±0.06 g/cm3 (Predicted)
Purity 98.0%
Pka
 		11.03±0.40 (Predicted)
Appearance Light yellow solid
Storage  2-8 °C, protected from light


References:

[1] Bermudez, J., Fake, C. S., Joiner, G. F., Joiner, K. A., King, F. D., Miner, W. D., & Sanger, G. J. (1990). 5-Hydroxytryptamine (5-HT3) receptor antagonists. 1. Indazole and indolizine-3-carboxylic acid derivatives. Journal of medicinal chemistry, 33(7), 1924-1929.

[2] Christie, L. A., Brice, N. L., Rowland, A., Dickson, L., Anand, R., Teall, M., ... & Bürli, R. W. (2023). Discovery of CVN417, a novel brain-penetrant α6-containing nicotinic receptor antagonist for the modulation of motor dysfunction. Journal of Medicinal Chemistry, 66(17), 11718-11731.