
Polysciences Inc. Poly(D,L-Lactide), IV 0.2 dL/g, Ester Terminated, Powder
SKU: 50321-5
Polysciences Inc. Poly(D,L-Lactide), IV 0.2 dL/g, Ester Terminated, Powder
MSE Supplies offers polymer reagents from Polysciences Inc.
Product Overview
High-grade, suitable for biomedical research.
Supplied as micronized powder.
Poly(DL-lactide) (PDLLA) is an ubiquitous biodegradable polymer. It is typically used to fabricate medical devices that predictably degrade over months in physiological conditions. The well-researched release profile also allows for drug-release functionalization with calculable results. Owing to its extensive history, PDLLA is one of the most understood and affordable biodegradable polymers for medical devices today.
Properties
Technical Specifications
Test | Specification |
Appearance | White powder |
Identity by 1H-NMR | Conforms to structure |
Inherent Viscosity (Chloroform) | 0.16 – 0.24 dL/g |
Residual Monomer | ≤ 0.5 % |
Residual Solvent | DMSO: ≤ 0.5 % |
Residual Solvent | Isopropanol: ≤ 0.5 % |
Acid Number | ≤ 6 mgKOH/g |
Residual Tin | ≤ 50 ppm |
Water Content | ≤ 0.5 % |
Residue on ignition | ≤ 0.1 % |
Total Aerobic Microbial Count | ≤ 100 CFU/g |
Total Yeasts / Molds Count | ≤ 100 CFU/g |
Bacterial Endotoxin | ≤ 0.1 EU/mg |
Molecular weight, Mw | Report value |
References
1. Martino, C., Kim, S.-H., Horsfall, L., Abbaspourrad, A., Rosser, S. J., Cooper, J., & Weitz, D. A. (2012). Protein Expression, Aggregation, and Triggered Release from Polymersomes as Artificial Cell-like Structures. Angewandte Chemie, 124(26), 6522–6526. doi:10.1002/ange.201201443
2.Middleton, J. C. & Tipton, A. J. Synthetic biodegradable polymers as orthopedic devices. Biomaterials 21, 2335–2346 (2000). doi:10.1016/S0142-9612(00)00101-0