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Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
SKU: E-AB-F09803A-25
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Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
| SKU # | E-AB-F09803A |
| Isotype | Mouse IgG2a, κ |
| Applications | FCM |
| Host | Mouse |
Product Details
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a, κ |
| Concentration | 1mg/mL |
| Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | C1.18.4 |
| Conjugation | Unconjugated |
Related Reagents
| Application | Products |
| WB | Western Blot Detection Kit(E-IR-R304) |
| IHC | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)(E-IR-R217) |
Background
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.