Total Price: $0.00
Contact Information
Recombinant Human ACY3 Protein (His Tag)
SKU: PKSH032781-50
Recombinant Human ACY3 Protein (His Tag)
| SKU # | PKSH032781 |
| Expression Host | E.coli |
Description
| Synonyms | ACY-3, ACY3, ASPA2, Acylase III, Aminoacylase-3, Aspartoacylase-2, HCBP1, HCV core-binding protein 1, Hepatitis C virus core-binding protein 1, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ser319 |
| Accession | Q96HD9 |
| Calculated Molecular Weight | 37.4 kDa |
| Observed Molecular Weight | 35 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member of the Aspartoacylase subfamily. ACY3 plays an important role in deacetylating mercapturic acids in kidney proximal tubules and acts on N-acetyl-aromatic amino acids.ACY3 is located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules. ACY3 protein is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein.