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Recombinant Human AIFM1 Protein (His Tag)
SKU: PKSH032089-50
Recombinant Human AIFM1 Protein (His Tag)
| SKU # | PKSH032089 |
| Expression Host | E.coli |
Description
| Synonyms | AIF, AIFM1, Apoptosis-Inducing Factor 1 Mitochondrial, PDCD8, Programmed Cell Death Protein 8 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Glu121-Asp613 |
| Accession | O95831 |
| Calculated Molecular Weight | 56.2 kDa |
| Observed Molecular Weight | 68 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, 2mM EDTA, 0.5M Argine, 5% Trehalose, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.