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Recombinant Human ALDOA protein (His tag)– MSE Supplies LLC

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Recombinant Human ALDOA protein (His tag)

SKU: PDEH100148-100

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Recombinant Human ALDOA protein (His tag)

 

SKU # PDEH100148
Expression Host E. coli

 

Description

Synonyms Fructose-Bisphosphate Aldolase A;Lung Cancer Antigen NY-LU-1;Muscle-Type Aldolase;ALDOA;ALDA
Species Human
Expression_host E.coli
Sequence Asp 18-Gly 273
Accession P04075
Mol_Mass 28.0 kDa
AP_Mol_Mass 32 kDa
Tag N-His
Bio_Activity Not validated for activity


Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis


Background

Fructose Bisphosphate Aldolase A (ALDOA) belongs to the class I fructose-bisphosphate aldolase family. ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, Aldolase A in muscle, Aldolase B in liver and aldolase C in brain. Aldolase A Interacts with SNX9 and WAS. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. In addition, Aldolase A plays an important role in glycolysis and gluconeogenesis; it may also act as a scaffolding protein.