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Recombinant Human Annexin A13/ANXA13 Protein
SKU: PKSH032073-50
Recombinant Human Annexin A13/ANXA13 Protein
| SKU # | PKSH032073 |
| Expression Host | E.coli |
Description
| Synonyms | ANX13, ANXA13, Annexin A13, Annexin XIII, Annexin-13, ISA, Intestine-Specific Annexin |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gly2-His316 |
| Accession | AAI25159.1 |
| Calculated Molecular Weight | 35.4 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Annexin A13 (ANXA13) belongs to the annexin family which plays a role in phospholipase inhibition, cytoskeletal interactions, intracellular signal transduction pathways and regulation of cellular growth. ANXA13 contains four annexin repeats and a pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA13 is highly expressed in intestinal and kidney epithelial cells. The specific function of ANXA13 has not yet been determined; however it is associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes.