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Recombinant Human Carbonic Anhydrase 14/CA14 Protein (E.coli, His Tag)
SKU: PKSH032160-50
Recombinant Human Carbonic Anhydrase 14/CA14 Protein (E.coli, His Tag)
| SKU # | PKSH032160 |
| Expression Host | E.coli |
Description
| Synonyms | CA-XIV, CA14, Carbonate Dehydratase XIV, Carbonic Anhydrase 14, Carbonic Anhydrase XIV, UNQ690/PRO1335 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gly19-Met290 |
| Accession | Q9ULX7 |
| Calculated Molecular Weight | 32.8 kDa |
| Observed Molecular Weight | 40 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Carbonic Anhydrase 14 (CA14) belongs to the Alpha-Carbonic Anhydrase family. It is highly expressed in all parts of the central nervous system and lowly expressed in adult liver, heart, small intestine, colon, kidney, urinary bladder, and skeletal muscle. CA14 along with other Carbonic Anhydrases (CAs) participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA14 is predicted to be a type I membrane protein and catalyzes the reversible hydration of carbon dioxide.