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Recombinant Human CLUL1 Protein (His Tag)
SKU: PKSH032262-50
Recombinant Human CLUL1 Protein (His Tag)
| SKU # | PKSH032262 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CLUL1, Clusterin-Like Protein 1, Retinal-Specific Clusterin-Like Protein |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala21-Ala442 |
| Accession | Q15846 |
| Calculated Molecular Weight | 50.1 kDa |
| Observed Molecular Weight | 59-75 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Clusterin-Like Protein 1 (CLUL1) is a secreted protein that belongs to the clusterin family. CLUL1 is synthesized as a 466 amino acid precursor that contains a 20 amino acid signal sequence, and a 446 amino acid mature chain. CLUL1 is expressed predominantly by cone photoreceptors of the retina. It has been shown that CLUL1 expression is down-regulated in some forms of retinal disease.