Recombinant Human Creatine Kinase, Muscle/CKM Protein (His Tag)
SKU: PKSH032285-50
Recombinant Human Creatine Kinase, Muscle/CKM Protein (His Tag)
SKU # | PKSH032285 |
Expression Host | HEK293 Cells |
Description
Synonyms | CKM, CKMM, Creatine kinase M chain, Creatine kinase M-type, M-CK |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Met 1-Lys381 |
Accession | AAP35439.1 |
Calculated Molecular Weight | 44.1 kDa |
Observed Molecular Weight | 46 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
Reconstitution | Not Applicable |
Background
Creatine kinase M-type is also known as Creatine kinase M chain,M-CK. It is a protein that in humans is encoded by the CKM gene. It belongs to the ATP:guanido phosphotransferase family,containing 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. Creatine kinase M-type can reversibly catalyzes the transfer of phosphate between ATP and various phosphogens. It plays a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.