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Recombinant Human CXCL10 Protein (Fc & His Tag)
SKU: PKSH032292-50
Recombinant Human CXCL10 Protein (Fc & His Tag)
| SKU # | PKSH032292 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | 10 kDa Interferon Gamma-Induced Protein, C-X-C Motif Chemokine 10, CXCL10, Gamma-IP10, INP10, IP-10, SCYB10, Small-Inducible Cytokine B10 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Val22-Pro98 |
| Accession | P02778 |
| Calculated Molecular Weight | 36.6 kDa |
| Observed Molecular Weight | 35 kDa |
| Tag | C-Fc-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.