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Recombinant Human CXCL3/GRO gamma Protein (His Tag)
SKU: PKSH032300-100
Recombinant Human CXCL3/GRO gamma Protein (His Tag)
| SKU # | PKSH032300 |
| Expression Host | E.coli |
Description
| Synonyms | C-X-C Motif Chemokine 3, CXCL3, GRO-Gamma, GRO-Gamma (1-73), GRO-Gamma (5-73), GRO3, GROG, Growth-Regulated Protein Gamma, MIP2-Beta, Macrophage Inflammatory Protein 2-Beta, SCYB3 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ala35-Asn107 |
| Accession | P19876 |
| Calculated Molecular Weight | 8.7 kDa |
| Observed Molecular Weight | 11 kDa |
| Tag | N-His |
| Bio-activity | Measure by its ability to chemoattract BaF3 cells transfected with human CXCR2.The ED50 for this effect is <2 ng/mL. |
Properties
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
C-X-C Motif Chemokine 3 (CXCL3) is a secreted protein that belongs to the intercrine alpha (chemokine CXC) family. CXCL3 controls the migration and adhesion of monocytes and mediates its effect on its target cell by interacting with a cell surface chemokine receptor called CXCR2. In addition, CXCL3 is thought to play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.