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Recombinant Human CXCL5 Protein– MSE Supplies LLC

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Recombinant Human CXCL5 Protein

Recombinant Human CXCL5 Protein

SKU: PKSH032303-100

  • $ 66595

Recombinant Human CXCL5 Protein

 

SKU # PKSH032303
Expression Host E.coli

 

 

Description

Synonyms C-X-C Motif Chemokine 5, CXCL5, ENA-78 (1-78), ENA-78 (8-78), ENA-78 (9-78), ENA78, Epithelial-Derived Neutrophil-Activating Protein 78, Neutrophil-Activating Peptide ENA-78, SCYB5, Small-Inducible Cytokine B5
Species Human
Expression Host E.coli
Sequence Arg 45-Asn114
Accession P42830
Calculated Molecular Weight 8.5 kDa
Observed Molecular Weight 12 kDa
Tag N-His
Bio-activity Measure by its ability to chemoattract BaF3 cells transfected with human CXCR2.The ED50 for this effect is <10 ng/mL.
  

 

Properties

Purity > 98 % as determined by reducing SDS-PAGE.
Endotoxin < 0.1 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.



Background

C-X-C Motif Chemokine 5 (CXCL5) is a member of the Intercrine Alpha (Chemokine CXC) family. CXCL5 can be cleaved into the following two chains, ENA-78 (8-78) and ENA-78 (9-78). In vitro, ENA-78(8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. CXCL5 is a secreted protein and exercises the functions primarily through interactions with CXCR2. The upregulation of CXCL5 contributes to increased vascularization, tumor grown, and metastasis in many cancers.