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Recombinant Human DCXR Protein (His Tag)
SKU: PKSH032714-50
Recombinant Human DCXR Protein (His Tag)
| SKU # | PKSH032714 |
| Expression Host | E.coli |
Description
| Synonyms | Carbonyl Reductase II, DCXR, Dicarbonyl/L-Xylulose Reductase, Kidney Dicarbonyl Reductase, L-Xylulose Reductase, Sperm Surface Protein P34H, XR, kiDCR |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Cys244 |
| Accession | Q7Z4W1 |
| Calculated Molecular Weight | 28.1 kDa |
| Observed Molecular Weight | 29 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 1mM DTT, 30% Glycerol, 1mM DTT, pH 8.0. |
| Reconstitution | Not Applicable |
Background
L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, α-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.