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Recombinant Human DHPS Protein (His Tag)
SKU: PKSH032349-50
Recombinant Human DHPS Protein (His Tag)
| SKU # | PKSH032349 |
| Expression Host | E.coli |
Description
| Synonyms | DHPS, DHS, DS, Deoxyhypusine Synthase |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Asp369 |
| Accession | P49366 |
| Calculated Molecular Weight | 42.0 kDa |
| Observed Molecular Weight | 42 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.