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Recombinant Human FABP2/I-FABP Protein (His Tag)
SKU: PDEH100012-100
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Recombinant Human FABP2/I-FABP Protein (His Tag)
| SKU # | PDEH100012 |
| Expression Host | E. coli |
Description
| Synonyms | Fatty Acid-Binding Protein Intestinal;Fatty Acid-Binding Protein 2;Intestinal-Type Fatty Acid-Binding Protein;I-FABP;FABP2;FABPI |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met1-Asp132 |
| Accession | P12104 |
| Mol_Mass | 18.4 kDa |
| AP_Mol_Mass | 17 kDa |
| Tag | N-His & C-His |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Fatty Acid-Binding Protein 2 (FABP2) is a cytoplasm protein that belongs to the Fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP2 is expressed in the small intestine and at much lower levels in the large intestine, the highest expression levels in the jejunum. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis and may also help maintain energy homeostasis by functioning as a lipid sensor.