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Recombinant Human FAM3C Protein (His Tag)
SKU: PKSH032962-50
Recombinant Human FAM3C Protein (His Tag)
| SKU # | PKSH032962 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | FAM3C, ILEI, Interleukin-Like EMT Inducer, Protein FAM3C |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln25-Asp227 |
| Accession | Q92520 |
| Calculated Molecular Weight | 23.2 kDa |
| Observed Molecular Weight | 20-25 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
FAM3C, also called interleukin-like EMT inducer, usually exist in most secretory epithelia. It belongs to the FAM3 family according to their sequence similarities. The up-regulation and/or mislocalization in breast cancer and liver carcinoma cells of FAM3C is strongly correlated with metastasis formation and survival. FAM3C can be involved in retinal laminar formation and promote epithelial to mesenchymal transition.