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Recombinant Human FAM3D Protein (His Tag)
SKU: PKSH032963-50
Recombinant Human FAM3D Protein (His Tag)
| SKU # | PKSH032963 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | FAM3D, Protein FAM3D |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Tyr26-Phe224 |
| Accession | Q96BQ1 |
| Calculated Molecular Weight | 23.1 kDa |
| Observed Molecular Weight | 26 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Reconstitution | Not Applicable |
Background
Protein FAM3D is a novel cytokine-like protein that belongs to the FAM3 family. Human FAM3D is synthesized as a 224 amino acid precursor that contains a 25 amino acid signal sequence and a 199 amino acid mature chain. FAM3D is identified based on structural, but not sequence, homology to short chain cytokines including IL-2, IL-4 and GM-CSF. FAM3 proteins are four helix bundle cytokines with four conserved cysteines in all members (FAM3A-D). FAM3B is highly expressed in alpha and beta cells of the pancreas and is being investigated as a potential contributor to beta cell death and development of Type I Diabetes.