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Recombinant Human Follitropin Subunit β/FSHB Protein (His Tag)
SKU: PKSH032456-50
Recombinant Human Follitropin Subunit β/FSHB Protein (His Tag)
| SKU # | PKSH032456 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | FSH-B, FSH-Beta, FSHB, Follicle-Stimulating Hormone Beta Subunit, Follitropin Beta Chain, Follitropin Subunit Beta |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Asn19-Glu129 |
| Accession | P01225 |
| Calculated Molecular Weight | 13.5 kDa |
| Observed Molecular Weight | 21 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD).