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Recombinant Human GAPDH Protein (His Tag)– MSE Supplies LLC

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Recombinant Human GAPDH Protein (His Tag)

SKU: PKSH031882-100

  • $ 65895



Recombinant Human GAPDH Protein (His Tag)

 

SKU # PKSH031882
Expression Host E.coli

 

 

Description

Synonyms G3PD, GAPD, HEL-S-162eP
Species Human
Expression Host E.coli
Sequence Met 1-Glu 335
Accession P04406
Calculated Molecular Weight 38 kDa
Observed Molecular Weight 38 kDa
Tag N-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 93 % as determined by reducing SDS-PAGE.
Endotoxin Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 50mM Tris, 30% glycerol, pH 7.5
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.



Background

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.