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Recombinant Human GLUL Protein (His Tag)
SKU: PKSH032494-50
Recombinant Human GLUL Protein (His Tag)
| SKU # | PKSH032494 |
| Expression Host | E.coli |
Description
| Synonyms | GLNS, GLUL, GS, Glutamate Decarboxylase, Glutamate--Ammonia Ligase, Glutamine Synthetase |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Thr 2-Asn373 |
| Accession | P15104 |
| Calculated Molecular Weight | 43.1 kDa |
| Observed Molecular Weight | 40-50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 50mM Imidazole, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency.