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Recombinant Human HAO1 Protein (His Tag)
SKU: PKSH033344-50
Recombinant Human HAO1 Protein (His Tag)
| SKU # | PKSH033344 |
| Expression Host | E.coli |
Description
| Synonyms | GOX, GOX1, Glycolate Oxidase, HAO1, HAOX1, Hydroxyacid Oxidase 1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ile370 |
| Accession | Q9UJM8 |
| Calculated Molecular Weight | 58.6 kDa |
| Observed Molecular Weight | 56 kDa |
| Tag | N-Trx-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.4. |
| Reconstitution | Not Applicable |
Background
Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent α-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate; but it can also be active on 2-Hydroxy fatty acids; with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.