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Recombinant Human HSF2 Protein (His Tag)
SKU: PKSH032521-50
Recombinant Human HSF2 Protein (His Tag)
| SKU # | PKSH032521 |
| Expression Host | E.coli |
Description
| Synonyms | HSF 2, HSF2, HSTF 2, HSTF2, Heat Shock Factor Protein 2, Heat Shock Transcription Factor 2 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ser411-Ser536 |
| Accession | Q03933 |
| Calculated Molecular Weight | 15.9 kDa |
| Observed Molecular Weight | 26 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. HSF2 is widely expressed in many cells and tissues. HSF2 is located on Cytoplasmic during normal growth. But when it is activited, HSF2 moves to the nucleus.