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Recombinant Human HSPA1A Protein (His Tag)
SKU: PDEH100015-100
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Recombinant Human HSPA1A Protein (His Tag)
| SKU # | PDEH100015 |
| Expression Host | E. coli |
Description
| Synonyms | heat shock protein family A (Hsp70) member 1A;heat shock protein family A (Hsp70) member 1B;HSP70-1B;HSP70-2;HSP70.2 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Ala2-Asp641 |
| Accession | P0DMV8-1 |
| Mol_Mass | 69.9 kDa |
| AP_Mol_Mass | 72.2 kDa |
| Tag | N-His |
Properties
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.