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Recombinant Human IL-20RA/IL-20R1 Protein (His Tag)(Active)
SKU: PKSH032576-50
Recombinant Human IL-20RA/IL-20R1 Protein (His Tag)(Active)
| SKU # | PKSH032576 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | UNQ, PRO, Cytokine Receptor Class-II Member, Cytokine Receptor Family 2 Member, CRF2, IL-20R, ZcytoR, CRF2-8, Cytokine Receptor Class-II Member 8, Cytokine Receptor Family 2 Member 8, IL-20 Receptor Subunit Alpha, IL-20R1, IL-20RA, IL-20R-Alpha, Interleukin-20 Receptor Subunit Alpha, ZcytoR7, IL20RA, UNQ681, PRO1315, alpha, class II cytokine receptor ZCYTOR7, CRF2 8, Cytokine receptor class II member 8, I20RA, IL 20R alpha, IL 20R1, Interleukin 20 receptor, Interleukin 20 receptor alpha chain, interleukin-20 receptor I |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Val30-Lys250 |
| Accession | Q9UHF4 |
| Calculated Molecular Weight | 26.3 kDa |
| Observed Molecular Weight | 35-50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide; a 221 amino acid extracellular domain with two fibronectin type-III domains; a 24 amino acid transmembrane region; and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB; and the complex serves as a receptor for IL19; IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.