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Recombinant Human IL-8/CXCL8 Protein (His Tag)
SKU: PDMH100011-100
Recombinant Human IL-8/CXCL8 Protein (His Tag)
| SKU # | PDMH100011 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CXCL, Interleukin, C-X-C motif chemokine, Chemokine (C-X-C motif) ligand, IL8/CXCL, GCP, NAP, CXCL8, GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, 3-10C, AMCF-I, IL8/CXCL8, K60, Interleukin-8, IL-8, Emoctakin, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Granulocyte chemotactic protein 1 (GCP-1), Monocyte-derived neutrophil chemotactic factor (MDNCF), (Ala-IL-8)77, (Ser-IL-8)72, 9E3, Beta thromboglobulin like protein, CEF-4, chemokine, CXC motif, GCP/IL-8 protein I, GCP/IL-8 protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, Granulocyte chemotactic protein 1, IL-8(1-77), IL-8(9-77), IL8/NAP1 form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 form V, IL8/NAP1 form VI, Inteleukin 8, ligand 8, Lymphocyte-derived neutrophil-activating factor, MDNCF-b, MDNCF-c, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, Neutrophil activating peptide 1, Neutrophil activating protein 1, Neutrophil-activating factor, Neutrophil-activating protein 1, Protein 3 10C, Protein 3-10C, SCYB8, Small inducible cytokine subfamily B member 8, T cell chemotactic factor, T-cell chemotactic factor, TSG1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Glu21-Ser99 |
| Accession | P10145 |
| Calculated Molecular Weight | 10.1 kDa |
| Observed Molecular Weight | 14 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types; including T cells; endothelial cells and fibroblasts; in response to an inflammatory stimulus and acts by recruiting neutrophils; T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.