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Recombinant Human MAP1LC3A Protein (His Tag)
SKU: PKSH032755-50
Recombinant Human MAP1LC3A Protein (His Tag)
| SKU # | PKSH032755 |
| Expression Host | E.coli |
Description
| Synonyms | Autophagy-Related Protein LC3 A, Autophagy-Related Ubiquitin-Like Modifier LC3 A, MAP1 Light Chain 3-Like Protein 1, MAP1A/MAP1B LC3 A, MAP1A/MAP1B Light Chain 3 A, Microtubule-Associated Protein 1 Light Cha, Microtubule-Associated Proteins 1A/1B Light Chain 3A |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Phe121 |
| Accession | Q9H492 |
| Calculated Molecular Weight | 15.3 kDa |
| Observed Molecular Weight | 18 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 100mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is absent in the thymus and peripheral blood leukocytes. MAP1LC3A is thought to take part in the formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. In addition, MAP1A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity.