Total Price: $0.00
Contact Information
Recombinant Human NRCAM Protein (Fc Tag)
SKU: PKSH033581-50
To better serve you, we would like to discuss your specific requirement.
Please Contact Us for a quote.
Recombinant Human NRCAM Protein (Fc Tag)
| SKU # | PKSH033581 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | KIAA0343, Neuronal cell adhesion molecule, Neuronal surface protein Bravo, Ng-CAM-related, Nr-CAM, gCAM-related cell adhesion molecule, gCAM-related cell adhesion molecule , hBravo |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln25-Asn600 |
| Accession | AAI15737.1 |
| Calculated Molecular Weight | 91.2 kDa |
| Observed Molecular Weight | 117 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration.