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Recombinant Human PLA2G16 Protein (His Tag)
SKU: PKSH032509-50
Recombinant Human PLA2G16 Protein (His Tag)
| SKU # | PKSH032509 |
| Expression Host | E.coli |
Description
| Synonyms | AdPLA, Adipose-Specific Phospholipase A2, Group XVI Phospholipase A1/A2, H-Rev 107 Protein Homolog, HRAS-Like Suppressor 1, HRAS-Like Suppressor 3, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3, PLA2G16, Renal Carcinoma Antigen NY-REN-65 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Asp12-Asp132 |
| Accession | P53816 |
| Calculated Molecular Weight | 14-17 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0. |
| Reconstitution | Not Applicable |
Background
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.