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Recombinant Human PMP2/FABP8 Protein (His Tag)
SKU: PKSH033587-50
Recombinant Human PMP2/FABP8 Protein (His Tag)
| SKU # | PKSH033587 |
| Expression Host | E.coli |
Description
| Synonyms | FABP8, M-FABP, Myelin P2 Protein, PMP2, Peripheral Myelin Protein 2 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met1-Val132 |
| Accession | P02689 |
| Calculated Molecular Weight | 17.1 kDa |
| Observed Molecular Weight | 14-20 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Citrate, 10% Trehalose, 100mM NaCl, 0.05% Tween 80, pH 4.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Myelin P2 Protein (PMP2) is a cytoplasmic protein which belongs to the Fatty-acid binding protein (FABP) family of calycin superfamily. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. PMP2 is found in peripheral nerve myelin and spinal cord myelin, the oligodendrocytes and Schwann cells, respectively. PMP2 may be involved in lipid transport protein in Schwann cells. It may decrease the inhibitory effect of T suppressors in the culture of immune lymph node cells.