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Recombinant Human PPP1CC Protein (His Tag)– MSE Supplies LLC

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Recombinant Human PPP1CC Protein (His Tag)

SKU: PKSH032969-50

  • $ 53395



Recombinant Human PPP1CC Protein (His Tag)

 

SKU # PKSH032969
Expression Host E.coli

 

 

Description

Synonyms PP-1G, PPP1CC, Protein Phosphatase 1C Catalytic Subunit, Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit
Species Human
Expression Host E.coli
Sequence Met 1-Lys323
Accession P36873
Calculated Molecular Weight 40.2 kDa
Observed Molecular Weight 30-40 kDa
Tag N-His & C-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 85 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, pH 8.0.
Reconstitution Not Applicable



Background

Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.