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Recombinant Human Pro-Neuropeptide Y/NPY Protein (His Tag)
SKU: PKSH032943-50
Recombinant Human Pro-Neuropeptide Y/NPY Protein (His Tag)
| SKU # | PKSH032943 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | C-Flanking Peptide of NPY, CPON, NPY, Neuropeptide Tyrosine, Neuropeptide Y, Pro-Neuropeptide Y |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Tyr29-Trp97 |
| Accession | P01303 |
| Calculated Molecular Weight | 9.1 kDa |
| Observed Molecular Weight | 13 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY can be cleaved into Neuropeptide Y and C-flanking peptide of NPY chain, which regulates energy usage, and it is involved in learning, memory processing, and epilepsy. NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. In addition, NPY increases the proportion of energy stored as fat and blocks nociceptive signals to the brain.