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Recombinant Human PUMA/BBC3 protein (His Tag)
SKU: PDEH100035-100
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Recombinant Human PUMA/BBC3 protein (His Tag)
| SKU # | PDEH100035 |
| Expression Host | E. coli |
Description
| Synonyms | BBC 3;Bbc3;BBC3_HUMAN;BCL 2 binding component 3;Bcl-2-binding component 3;BCL2 binding component 3;JFY 1;JFY-1;JFY1;p53 up regulated modulator of apoptosis;p53 up-regulated modulator of apoptosis;p53 Upregulated Modulator of Apoptosis;PUMA alpha;PUMA/JFY1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met1-Asn193 |
| Accession | Q9BXH1-1 |
| Mol_Mass | 20.1 kDa |
| AP_Mol_Mass | 20-24 kDa |
| Tag | N-His |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4.5% trehalose, 5% mannitol, 0.01% Tween 80. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.