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Recombinant Human RAB38 protein (His tag)– MSE Supplies LLC

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Recombinant Human RAB38 protein (His tag)

Recombinant Human RAB38 protein (His tag)

SKU: PDEH100349-100

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Recombinant Human RAB38 protein (His tag)

 

SKU # PDEH100349
Expression Host E. coli

 

Description

Synonyms RAB38;Ras-related protein Rab-38;Melanoma antigen NY-MEL-1
Species Human
Expression_host E.coli
Sequence Met 1-Ser 211
Accession P57729
Mol_Mass 23.1 kDa
AP_Mol_Mass 29 kDa
Tag N-His & C-His
Bio_Activity Not validated for activity


Propertie

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis


Background

May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).