Total Price: $0.00
Contact Information
Recombinant Human RANTES protein (GST&His tag)
SKU: PDEH100220-100
To better serve you, we would like to discuss your specific requirement.
Please Contact Us for a quote.
Recombinant Human RANTES protein (GST&His tag)
| SKU # | PDEH100220 |
| Expression Host | E. coli |
Description
| Synonyms | C-C Motif Chemokine 5;EoCP;Eosinophil Chemotactic Cytokine;SIS-Delta;Small-Inducible Cytokine A5;T Cell-Specific Protein P228;TCP228;T-Cell-Specific Protein RANTES;CCL5;D17S136E;SCYA5 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Pro 25-Ser 91 |
| Accession | P13501 |
| Mol_Mass | 32.3 kDa |
| AP_Mol_Mass | 42 kDa |
| Tag | N-GST & C-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.