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Recombinant Human REG4/RELP Protein (His Tag)
SKU: PKSH032991-50
Recombinant Human REG4/RELP Protein (His Tag)
| SKU # | PKSH032991 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | GISP, Gastrointestinal secretory protein, REG-IV, REG-like protein, REG4, RELP, Regenerating islet-derived protein 4, Regenerating islet-derived protein IV |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Asp23-Pro158 |
| Accession | Q9BYZ8 |
| Calculated Molecular Weight | 19.2 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
REG4 is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. REG4 can be up-regulated by mucosal injury from active Crohn’s disease or ulcerative colitis. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium.