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Recombinant Human ROBO4 Protein (Fc Tag)
SKU: PKSH033348-50
Recombinant Human ROBO4 Protein (Fc Tag)
| SKU # | PKSH033348 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Magic roundabout, ROBO4, Roundabout homolog 4, UNQ421/PRO3674 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln28-Arg467 |
| Accession | Q8WZ75 |
| Calculated Molecular Weight | 74.6 kDa |
| Observed Molecular Weight | 87 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Roundabout homolog 4(ROBO4) contains 2 fibronectin type-III domains; 2 Ig-like C2-type (immunoglobulin-like) domains and belongs to the immunoglobulin superfamily.The protein is a receptor for slit proteins; at least for SLIT2; and seems to be involved in angiogenesis and vascular patterning. ROBO4 may mediate the inhibition of primary endothelial cell migration by Slit proteins.