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Recombinant Human S100A9 Protein
SKU: PKSH033380-50
Recombinant Human S100A9 Protein
| SKU # | PKSH033380 |
| Expression Host | E.coli |
Description
| Synonyms | CAGB, CFAG, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, MRP-14, Protein S100-A9 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Thr 2-Pro114 |
| Accession | P06702 |
| Calculated Molecular Weight | 13.2 kDa |
| Observed Molecular Weight | 14 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Protein S100-A9 (also MRP14 and calgranulin B)is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism.