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Recombinant Human SCLY Protein (His Tag)
SKU: PKSH033015-50
Recombinant Human SCLY Protein (His Tag)
| SKU # | PKSH033015 |
| Expression Host | E.coli |
Description
| Synonyms | SCL, SCLY, Selenocysteine Lyase, hSCL |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ala445 |
| Accession | Q96I15 |
| Calculated Molecular Weight | 50.3 kDa |
| Observed Molecular Weight | 50-55 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Selenocysteine Lyase belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Selenocysteine Lyase exists as a homodimer in the cytosol. In the brain, Selenocysteine Lyase is as an enzyme that putatively salvages Sec and recycles the selenium for selenoprotein translation. Selenocysteine Lyase catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. Selenocysteine Lyase can be up-regulated In acute glomerulonephritis, it can also be regulated by JUN/AP-1.