Recombinant Human SELL Protein (His Tag)
SKU: PKSH033351-50
Recombinant Human SELL Protein (His Tag)
SKU # | PKSH033351 |
Expression Host | HEK293 Cells |
Description
Synonyms | CD62 antigen-like family member L, CD62L, L-selectin, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, PLNHR, TQ1, gp90-MEL |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Trp39-Asn332 |
Accession | P14151 |
Calculated Molecular Weight | 34.0 kDa |
Observed Molecular Weight | 60 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background
SELL contains one C-type lectin domain; one EGF-like domain and two Sushi (CCP/SCR) domains. SELL is expressed in B-cell lines and T-lymphocytes. SELL functions as a cell surface adhesion protein and mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. In addition; SELL also promotes initial tethering and rolling of leukocytes in endothelia.