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Recombinant Human Semaphorin 3C/SEMA3C Protein (His Tag)
SKU: PKSH033017-50
Recombinant Human Semaphorin 3C/SEMA3C Protein (His Tag)
| SKU # | PKSH033017 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | SEMA3C, SEMAE, Sema E, Semaphorin-3C, Semaphorin-E |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gly21-Ser738 |
| Accession | Q99985 |
| Calculated Molecular Weight | 82.4 kDa |
| Observed Molecular Weight | 75-120&27KD |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM NaH2PO4, 150mM NaCl, 0.1M Arginine, 0.1M Glu, 10% Glycerol, 0.01% Tween20, 5% Trehalose, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary and prostate, expressed lowly in the other organs, including the brain.