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Recombinant Human SIGLEC9/CD329 Protein (Fc Tag)
SKU: PKSH033055-50
Recombinant Human SIGLEC9/CD329 Protein (Fc Tag)
| SKU # | PKSH033055 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CDw329, Protein FOAP-9, SIGLEC9, Sialic acid-binding Ig-like lectin 9, Siglec-9 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln18-Gly348 |
| Accession | AAH35365.2 |
| Calculated Molecular Weight | 63.2 kDa |
| Observed Molecular Weight | 90-120 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils); and found in liver; fetal liver; bone marrow; placenta; spleen and in lower levels in skeletal muscle; fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2;3- or alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.