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Recombinant Human ST6GALNAC2 Protein (His Tag)
SKU: PKSH033078-50
Recombinant Human ST6GALNAC2 Protein (His Tag)
| SKU # | PKSH033078 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | 6-Sialyltransferase 2, 6-Sialyltransferase II, Alpha-N-Acetylgalactosaminide Alpha-2, GalNAc Alpha-2, SIAT7-B, SIAT7B, SIATL1, ST6GALNAC2, ST6GalNAc II, ST6GalNAcII, STHM, SThM, Sialyltransferase 7B |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ser29-Arg374 |
| Accession | Q9UJ37 |
| Calculated Molecular Weight | 38.8 kDa |
| Observed Molecular Weight | 44 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, 5% Trehalosen, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modifications play roles in cell-cell and cell-substrate interactions, bacterial adhesion and protein targeting. ST6GALNAC2 is localized to the Golgi apparatus membrane. ST6GALNAC2 is highly expressed in lactating mammary glands and the adult testis; it is expressed at lower levels in the kidney. ST6GALNAC2 can catalyze 2,6-sialylation of the Tn antigen.