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Recombinant Human STEAP3 protein (GST,His tag)
SKU: PDEH100429-100
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Recombinant Human STEAP3 protein (GST,His tag)
| SKU # | PDEH100429 |
| Expression Host | E. coli |
Description
| Synonyms | Metalloreductase STEAP3;STEAP3;Six-transmembrane epithelial antigen of prostate 3 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met1-Thr258 |
| Accession | Q658P3 |
| Mol_Mass | 53.3 kDa |
| AP_Mol_Mass | 55 kDa |
| Tag | N-GST & C-His |
| Bio_Activity | Not validated for activity |
Propertie
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.