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Recombinant Human STK24/MST3 Protein (His Tag)(Active)
SKU: PKSH030330-50
Recombinant Human STK24/MST3 Protein (His Tag)(Active)
| SKU # | PKSH030330 |
| Expression Host | Baculovirus-Insect Cells |
Description
| Synonyms | HEL-S-95, MST3, MST3B, RP11-111L24.5, STE20, STK3 |
| Species | Human |
| Expression Host | Baculovirus-Insect Cells |
| Sequence | Met 1-His 431 |
| Accession | Q9Y6E0-2 |
| Calculated Molecular Weight | 50.3 kDa |
| Observed Molecular Weight | 55 kDa |
| Tag | N-His |
| Bio-activity | The specific activity was determined to be 62 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate. |
Properties
| Purity | > 82 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as sterile solution of 50mM Tris, 100mM NaCl, pH 8.0, 20% glycerol, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT |
| Reconstitution | Not Applicable |
Background
MST3 encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.