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Recombinant Human SULT2A1 Protein (His Tag)
SKU: PKSH033368-50
Recombinant Human SULT2A1 Protein (His Tag)
| SKU # | PKSH033368 |
| Expression Host | E.coli |
Description
| Synonyms | Bile Salt Sulfotransferase, DHEA-ST, DHEAS, Dehydroepiandrosterone Sulfotransferase, HST, Hydroxysteroid Sulfotransferase, ST2, ST2A1, ST2A3, STD, SULT2A1, Sulfotransferase 2A1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ser2-Glu285 |
| Accession | Q06520 |
| Calculated Molecular Weight | 35.2 kDa |
| Observed Molecular Weight | 34-38 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Bile Salt Sulfotransferase (SULT2A1( is a cytosolic enzyme that belongs to the Sulfotransferase 1 family. SULT2A1 is primarily expressed in the liver and adrenal tissues, and to a lesser extent in the kidney. SULT2A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor, and it catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. SULT2A1 may have a role in the inherited adrenal androgen excess.